1. Herniated nucleus pulposus is removed by way of a surgical instrument. 2. The nucleus pulposus of the intervertebral disk has no pain innervation. 3. The nucleus pulposus and the fibers of the anulus fibrosus make up the intervertebral disc. 4. A postembryonic vestige of the notochord is found in the nucleus pulposus of the intervertebral discs. 5. Fibrocartilage replaces the gelatinous mucoid material of the nucleus pulposus as the disc changes with age. 6. There may be splits in the anulus fibrosus, permitting herniation of elements of nucleus pulposus . 7. One generally refers to the gradual dehydration of the " nucleus pulposus " as degenerative disc disease. 8. With degeneration the contents of the disc, the nucleus pulposus and anulus fibrosus, are exposed to altered loads. 9. If the extruded nucleus pulposus material doesn't press on soft tissues or nerves, it may not cause any symptoms. 10. A review article on the subject discusses the use of hydrogels for nucleus pulposus replacement, cartilage replacement, and synthetic tissue models.
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